Integration Across the Lifespan Domain Task Force

Translational science is integrated across its multiple phases and disciplines within complex populations and across the individual lifespan. This Domain Task Force focuses on:
  • Integrating translational science across the entire lifespan to attain improvements in health for all.
  • Launching efforts to study special population differences in the progress and treatment of disease processes.
  • Developing a seamless integrated approach to translational science across all phases of research.

Leadership

Name (CTSA Hub / Institution)
Role
Shari Barkin (Vanderbilt) Co-Lead
Dan Cooper (University of California, Irvine) Co-Lead (Steering Committee Appointee)
Peter Szilagyi (UCLA) Lead Team
Rosalind Wright (Mt. Sinai) Lead Team
Christina Chambers (UCSD) Lead Team
Mary Purucker (NCATS) NCATS/DCI Representative

Membership

Last Name
First Name
CTSA Hub / Institution
Alcorn Michael Scripps Research Institute
Allison Jeroan University of Massachusetts Medical School, Worcester
Armstrong Daniel University of Miami
Atkins Marc University of Illinois at Chicago
Bandeen Karen Johns Hopkins University
Biggio Joseph The University of Alabama at Birmingham
Brazhnik Olga NIH/NCATS/DCI
Brooks PJ NCATS/DCI
Burnett Jason University of Texas Health Science Center at Houston
Cardarelli Roberto University of Kentucky Research Foundations
Chambers Christina University of California, San Diego
Chapman Arlene University of Chicago
Cody Jannine The University of Texas Health Sciences Center at San Antonio
Davis Sonia The University of North Carolina at Chapel Hill
deBerardinis Ralph University of Texas Southwestern Medical Center at Dallas
Denne Scott Indiana University School of Medicine
Dozier Ann University of Rochester School of Medicine and Dentistry
Drezner Marc University of Wisconsin - Madison
Garten Larry Cystic Fibrosis Foundation
Gleason Christine March of Dimes
Goodman Elizabeth Harvard University
Green Nancy Columbia University
Guay-Woodford Lisa Children's National Medical Center
Hadley Evan NIH/NIA
Hay Bill University of Colorado Denver
Holbein Blair UT Southwestern
Hughes-Halbert Chanita Medical University of South Carolina
Huskins Charles Mayo Clinic
James Laura University of Arkansas for Medical Sciences
Johnson Tesheia Yale University
Kaiser Jim FDA/CDER Office of Translational Science
Karagas Margaret Dartmouth College
Kaskel Frederick Albert Einstein College of Medicine
Kipke Michele University of Southern California
Konstan Michael Case Western Reserve University
Kritchevsky Stephen Wake Forest Baptist Medical Center
Leonard Mary Stanford University
Leuenberger Urs Penn State Milton S. Hershey Medical Center
Li Jennifer Duke University
Lubin Bertram University of California, San Francisco
Marcus Carole University of Pennsylvania
McColley Susanna Northwestern University
Mellman Thomas Georgetown University with Howard University
Peschin Susan Alliance for Aging Research
Quattrin Teresa University of Buffalo
Reis Steven University of Pittsburgh
Samuels Mary Oregon Health and Science University
Schleiss Mark University of Minnesota
Schultz Susan University of Iowa
Shapiro Eugene Yale University
Sehgal Lota Kanchan University of Michigan
Shenkman Elizabeth University of Florida
Sherman Scott New York University School of Medicine
Silverstein Michael Boston University
Smoyer William The Ohio State University
Stark Susan Washington University
Tobin Jonathan The Rockefeller University
Truog William University of Kansas Medical Center
Urv Tiina NCATS/DCI
Verbsky James Medical College of Wisconsin
Volpi Elena University of Texas Medical Branch
Ward Mary Jo Weill Cornell Medical College
Wetmore Cynthia Emory University
Wilfond Benjamin University of Washington
Winter Stuart University of New Mexico Health Sciences Center
Wun Ted University of California, Davis

Meeting Schedule:

3rd Thursday of every other month at 2pm CT / 3pm ET

Workgroups:

  1. Early Life Exposure: Co-led by Shari Barkin of Vanderbilt and Heidi Hanson of University of Utah, this group will investigate the relationship between  environmental exposures and developmental outcomes. Currently, the group is determining how best to identify and leverage existing longitudinal cohorts at CTSA Program hubs and are exploring possible synergies and collaborative opportunities with PCORnet.
  2. Aging: This group, which is co-led by Karen Bandeen-Roche, Ph.D., of Johns Hopkins University and Elena Volpi, M.D., Ph.D., of the University of Texas Medical Branch, has discussed several potential projects including   identification of biomarkers predictive of frailty, strategies to improve the recruitment and retention of older adults (>75 years) into clinical trials, and how to leverage home health monitoring for collection of research data.  Regarding the latter project, the group plans to seek input from the broader community conducting aging-related research.
  3. Single Disease: This group, which is co-led by Nancy Green, M.D., of Columbia University and Jannine Cody, Ph.D.,  of the University of Texas Health Science Center at San Antonio, will investigate single diseases projected across the lifespan with the goal of better understanding the progress of the disease as well as critical transitions. Such information might be used to design a natural history study, develop age-appropriate outcome measures, or to develop protocols to improve the transition of clinical care such as between pediatric and adult patients.  The group will initially focus on sickle cell disease and may later expand to include cystic fibrosis and other diseases.  The group is considering is developing a clinical database that spans CTSA Program hubs using electronic health records.

Contact:

lifespan@ctsac4.org